Vol. 5, Issue 1, Part A (2023)

Hepatitis E virus (HEV) is a significant cause of viral hepatitis worldwide, with distinct genotypes exhibiting varying patterns of distribution and epidemiology. This study compares the major HEV genotypes and analyzes their global distribution based on data collected from multiple regions. Through the analysis of genotype-specific characteristics, this paper explores the epidemiological trends, transmission routes, and public health implications associated with each genotype. Data were collected from 2015 to 2020, highlighting shifts in genotype prevalence and distribution patterns. Significant findings reveal genotype-specific trends linked to socioeconomic, environmental, and host factors.